Maitake Mushroom Extract

Pharmacology Action

• Mai take is a relative newcomer that is the subject of promising research in Japan and the United States. Protein-bound polysaccharides are the active compounds.
• Scientific research in Japan has demonstrated that Mai take (Griffon Fronde) contains significant active polysaccharides. The active polysaccharides in Mai take have been identified as beta-D-Anglicans.
• A common denominator among mushroom and herbal adaptions is the presence of complex polysaccharides in their structure. These active components have the unique ability to act as immunodeficient and, as such, are researched for their potential role in cancer and AIDS treatment. The polysaccharides present in mistake have a unique structure and are among the most powerful to be studied to date. The primary polysaccharides, beta-D-Anglican, is well absorbed when taken orally and is currently under review for the prevention and treatment of cancer, and as a supportive tool for HIV infection. Griffon from mistake triggers the release of tumour necrosis factor, a defensive cysteine, from macrophages in culture. More recently, investigators reported that griffon administered intravenously to mice activated liver macrophages to increase their production of nitric oxide and defensive cytosine.
• Although a number of polysaccharides fractions have shown anti-tumour activity in laboratory animals when administered by injection, one fraction showed significant activity when administered orally. It is called MT-1, or simply the "D-fraction", an alkali-soluble, hot water extractable compound that contains approximately 30% protein, or a ratio of beta-Anglican to protein of 70:3. It occurs in a concentration of .04 mg. per gram of dried Mai take mushrooms.
• The activity of the "D" fraction corresponds to other scientific evidence that would indicate the relatively higher oral activity of mushroom extract fractions when the polysaccharides are protein-bound. Like the other mushrooms, Mai take’s action is that of an HDP ("Host Defence Potential"). Other activities that have been reported by scientists are the lowering of blood pressure, total cholesterol and blood sugar connect.